Laccase-catalyzed stereoselective oxidative ring opening of 2,5-dialkylfurans into 2-ene-1,4-diones using air as an oxidant.
- Publikations-Art
- Zeitschriftenbeitrag (peer-reviewed)
- Autoren
- Asta, C.; Conrad, J.; Mika, S.; Beifuss, U.
- Erscheinungsjahr
- 2011
- Veröffentlicht in
- Green Chem.
- Band/Volume
- 13/11
- DOI
- 10.1039/c1gc15810d
- Seite (von - bis)
- 3066-3069
The laccase-catalyzed ring opening of 2,5-dimethylfuran using air as an oxidant stereoselectively yields (Z)- or (E)-3-hexene-2,5-dione depending on the mediator employed: with TEMPO the (Z)-3-hexene-2,5-dione is formed, while a combination of TEMPO and violuric acid gives (E)-3-hexene-2,5-dione.The (Z)-selective ring cleavage was extended to a variety of symmetrical and unsymmetrical 2,5-dialkylfurans.