Relationship between bichiral amino alcohol (salicylaldimino) copper complexes and enantioselectivities of cyclopropanation

Publikations-Art

Zeitschriftenbeitrag

Autoren

Wang, M.; Hu, B.-F.; Kraus, W.

Erscheinungsjahr

1996

Veröffentlicht in

Gaodeng Xuexiao Huaxue Xuebao

Band/Volume

17/1

Seite (von - bis)

65-8

The enantioselective cyclopropanation of olefins and Et diazoacetate under salicylaldehyde bichiral amino alc. (PhCHOHCHMeNH2) Schiff base copper complexes was studied. The results show that the main effect on the enantioselectivity is the configuration of the carbon attached to nitrogen atom, the R-(N-C)-configuration catalyst produces the excess of the 1R-cyclopropane product and the S-(N-C)-configuration catalyst produces the excess of the 1S-cyclopropane product. The configuration of the carbon attached to oxygen atom also has effect on the enantioselectivity of reaction, but this is not the major one.