Short total synthesis of the spiro[4.5]decane sesquiterpene (-)-gleenol
- Publikations-Art
- Zeitschriftenbeitrag
- Autoren
- Oesterreich, K.; Spitzner, D
- Erscheinungsjahr
- 2002
- Veröffentlicht in
- Tetrahedron
- Band/Volume
- 58/21
- Seite (von - bis)
- 4331-4334
The spirocyclic sesquiterpene (-)-gleenol (I) was prepd. in five steps starting from (-)-menthone via a di-olefin. The final spiro-ring system was made using the olefin metathesis reaction. The resulting ketone was selectively reduced to the natural product.