Publikationen: Fg. Biofunktionalität der Lebensmittel

Titel	Jahr	Publikationsart	Autoren
The long chain α–tocopherol metabolite α‐13’‐COOH and γ‐tocotrienol induce P‐glycoprotein expression and activity by activation of the pregnane X receptor in the intestinal cell line LS 180 Molecular Nutrition food research	2017	Zeitschriftenbeitrag (peer-reviewed)	Maren C. Podszun, Metta Jakobi, Marc Birringer, Johanna Weiss, Jan Frank
Transepithelial Transport of Curcumin in Caco-2 Cells Is significantly Enhanced by Micellar Solubilisation	2017	Zeitschriftenbeitrag (peer-reviewed)	Jan Frank, Christina Schiborr, Alexa Kocher, Jürgen Meins, Dariush Behnam, Manfred Schubert-Zsilavecz, Mona Abdel-Tawab
Effects of long-term Rice Bran Extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice NeuroMolecular Medicine	2016	Zeitschriftenbeitrag (peer-reviewed)	Hagl, S., Asseburg, H., Heinrich, M., Sus, N., Blumrich, E.-M., Dringen, R., Frank, J. & Eckert, G. P
Effects of Long-Term Rice Bran Extract Supplementation on Survival, Cognition and Brain Mitochondrial Function in Aged NMRI Mice NeuroMolecular Medicine	2016	Zeitschriftenbeitrag (peer-reviewed)	Stephanie Hagl, Heike Asseburg, Martina Heinrich, Nadine Sus, Eva-Maria Blumrich, Ralf Dringen, Jan Frank, Gunter P. Eckert
Highly bioavailable micellar curcuminoids accumulate in blood, are safe and do not reduce blood lipids and inflammation markers in moderately hyperlipidaemic individuals Molecular Nutrition & Food Research	2016	Zeitschriftenbeitrag (peer-reviewed)	Alexa Kocher, Laura Bohnert, Christina Schiborr andJan Frank
Intratumoral concentrations and effects of orally administered micellar curcuminoids in glioblastoma patients Nutrition and Cancer	2016	Zeitschriftenbeitrag (peer-reviewed)	Dützmann, S., Schiborr, C., Kocher, A., Pilatus, U., Hattingen, E., Weissenberger, J., Gessler, F., Quick-Weller, J., Franz, K., Seifert, V., Frank, J. & Senft, C.
Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients Nutrition and Cancer	2016	Zeitschriftenbeitrag (peer-reviewed)	Stephan Dützmann, Christina Schiborr, Alexa Kocher, Ulrich Pilatus, Elke Hattingen, Jakob Weissenberger, Florian Geßler, Johanna Quick-Weller, Kea Frankz, Volker Seifert, Jan Frank & Christian Senft
Intratumoral Concentrations and Effects of Orally Administered Micellar Curcuminoids in Glioblastoma Patients Nutrition and Cancer	2016	Zeitschriftenbeitrag (peer-reviewed)	Stephan Dützmann, Christina Schiborr, Alexa Kocher, Ulrich Pilatus, Elke Hattingen, Jakob Weissenberger, Florian Geßler, Johanna Quick-Weller, Kea Franz, Volker Seifert, Jan Frank & Christian Senft
Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice Nutritional Neuroscience	2016	Zeitschriftenbeitrag (peer-reviewed)	Stephanie Hagl*, Dirk Berressem, Rehka Grewal, Nadine Sus, Jan Frank & Gunter P. Eckert
The effect of conjugated linoleic acid supplements on oxidative and antioxidative status of dairy cows Journal of Dairy Science	2016	Arbeitspapier/Diskussionspapier	N.Hanschke, M.Kankofer, L.Ruda*M.Höltershinken, U.Meyer, J.Frank, S.Dänicke, J.Rehage
Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components Molecules	2015	Zeitschriftenbeitrag (peer-reviewed)	Stephanie Hagl, Dirk Berressem , Bastian Bruns , Nadine Sus, Jan Frank and Gunter P. Eckert
Concentrations of total curcuminoids in plasma, but not liver and kidney, are higher in 18- than in 3-months old mice NFS Journal	2015	Zeitschriftenbeitrag (peer-reviewed)	Alexa Kocher, Stephanie Hagl, Christina Schiborr, Gunter P. Eckert, Jan Frank
Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice – Impact on bioavailability Neurochemistry International	2015	Zeitschriftenbeitrag (peer-reviewed)	Stephanie Hagl, Alexa Kocher, Christina Schiborr, Natalie Kolesova, Jan Frank, Gunter P. Eckert
Effects of curcumin in pediatric epithelial liver tumors: inhibition of tumor growth and alpha-fetoprotein in vitro and in vivo involving the NFkappaB- and the beta-catenin pathways Impact Journals Oncotarget	2015	Zeitschriftenbeitrag (peer-reviewed)	Nicola Bortel, Sorin Armeanu-Ebinger, Evi Schmid, Bettina Kirchner, Jan Frank, Alexa Kocher, Christina Schiborr, Steven Warmann, Jörg Fuchs, Verena Ellerkamp
Non-targeted 1H-NMR-metabolomics suggest the induction of master regulators of energy metabolism in the liver of vitamin E-deficient rats Food Funct.	2015	Zeitschriftenbeitrag (peer-reviewed)	Ali A. Moazzami,*a Sonja Frank,b Antonin Gombert Nadine Sus, Banu Bayram Gerald Rimbach, and Jan Frank
The oral bioavailability of curcuminoids in healthy humans is markedly enhanced by micellar solubilisation but not further improved by simultaneous ingestion of sesamin, ferulic acid, naringenin and xanthohumol Journal of Functional Foods	2015	Zeitschriftenbeitrag (peer-reviewed)	Alexa Kochera, Christina Schiborra, Dariush Behnamb, Jan Frank
Tocopherols and tocotrienols in serum and liver of dairy cows receiving conjugated linoleic acids or a control fat supplement during early lactation Journal of Dairy Science	2015	Arbeitspapier/Diskussionspapier	H. Sadri, S. Dänicke, Ulrich Meyer, J. Rehage, J. Frank, H. Sauerwein
Adenosine triphosphate concentrations are higher in the brain of APOE3- compared to APOE4-targeted replacement mice and can be modulated by curcumin Genes & Nutrition	2014	Zeitschriftenbeitrag (peer-reviewed)	Dawn Chin, Stephanie Hagl, Annika Hoehn, Patricia Huebbe, Kathrin Pallauf, Tilman Grune, Jan Frank, Gunter P. Eckert, Gerald Rimbach
Curcumin may impair iron status when fed to mice for six months Redox Biology	2014	Arbeitspapier/Diskussionspapier	Dawn Chin, Patricia Huebbea, Jan Frankb, Gerald Rimbacha, Kathrin Pallauf
CURCUMIN MICELLES IMPROVE MITOCHONDRIAL FUNCTION IN A MOUSE MODEL OF ALZHEIMER’S DISEASE he Journal of Prevention of Alzheimer’s Disease	2014	Zeitschriftenbeitrag (peer-reviewed)	S. Hagl, M. Heinrich, A. Kocher, C. Schiborr, J. Frank, G.P. Eckert
Dietary α-tocopherol and atorvastatin reduce high-fat-induced lipid accumulation and down-regulate CD36 protein in the liver of guinea pigs The Journal of Nutritional Biochemistry	2014	Zeitschriftenbeitrag (peer-reviewed)	Maren C. Podszuna, Nadine Grebensteina, Astrid Sprussb, Thomas Schlueterc, Claus Kremoserc, Ina Bergheimb, Jan Frank
Dietary exposure to continuous small doses of α-cypermethrin in the presence or absence of dietary curcumin does not induce oxidative stress in male Wistar rats	2014	Zeitschriftenbeitrag (peer-reviewed)	Surat Hongsibsonga, b, Wolfgang Stuetz, b, c, Nadine Sus, Tippawan Prapamontol, Tilman Grune, Jan Frank
Rapid Method for Glutathione Quantitation Using High-Performance Liquid Chromatography with Coulometric Electrochemical Detection J.Agric. food Chem	2014	Zeitschriftenbeitrag (peer-reviewed)	Banu Bayram, Gerald Rimbach, Jan Frank, Tuba Esatbeyoglu
The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes Molecular Nutrition & Food Research	2014	Zeitschriftenbeitrag (peer-reviewed)	Christina Schiborr, Alexa Kocher, Dariush Behnam, Josef Jandasek, Simone Toelstede andJan Frank
The use of total antioxidant capacity as surrogate marker for food quality and its effect on health is to be discouraged Nutrition	2014	Zeitschriftenbeitrag	Pompella A, Sies H, Wacker R, Brouns F, Grune T, Biesalski HK, Frank J
Vitamin E-drug interactions - molecular basis and clinical relevance. Nutrition Research Reviews (NUTR RES REV)	2014	Weitere Veröffentlichung	Podszun, M. C. & Frank, J.
α-Tocopherol transfer protein is not required for the discrimination against γ-tocopherol in vivo but protects it from side-chain degradation in vitro Mol Nutr Food Res	2013	Zeitschriftenbeitrag	Grebenstein N, Schumacher M, Graeve L, Frank J
Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU- induced oxidative stress and cell death Apoptosis	2013	Zeitschriftenbeitrag	Mohrenz IV, Antonietti P, Pusch S, Capper D, Balss J, Voigt S, Weissert S, Mukrowsky A, Frank J, Senft C, Seifert V, vom Deimling A, Koegel D
Rice bran extract protects from mitochondrial dysfunction in guinea pig brains Pharmacol Res	2013	Arbeitspapier/Diskussionspapier	Hagl S, Kocher A, Schiborr C, Eckert S, Ciobanu I, Birringer M, El-Askary H, Helal A, Khayyal MT, Frank J, Müller WE, Eckert GP
The oral bioavailability of curcumin from micronized powder and liquid micelles is significantly increased in healthy humans and differs between sexes Mol Nutr Food Res	2013	Zeitschriftenbeitrag	Schiborr C, Behnam D, Jandasek J, Toelstede S, Frank J
The senescence-accelerated mouse - prone 8 is not a suitable model for the investigation of cardiac inflammation and oxidative stress and their modulation by dietary phytochemicals Pharmacol Res	2013	Zeitschriftenbeitrag	Schiborr C, Schwamm D, Kocher A, Rimbach G, Eckert GP, Frank J
Combination of PDT and inhibitor treatment affects melanoma cells and spares keratinocytes Free Radic Biol Med	2011	Zeitschriftenbeitrag	Kästle M, Grimm S, Nagel R, Breusing N, Grune T
The outcome of 5-ALA-mediated photodynamic treatment in melanoma cells is influenced by vitamin C and heme oxygenase-1 Biofactors	2011	Zeitschriftenbeitrag	Grimm S, Mvondo D, Grune T, Breusing N
Effects of dietary phenolic compounds on tocopherol, cholesterol, and fatty acids in rats Lipids	2000	Zeitschriftenbeitrag	Kamal-Eldin A, Frank J, Razdan A, Tengblad S, Basu S, Vessby B
ATP-sensitive K+ channel modulator binding to sulphonylurea receptors SUR2A and SUR2B: Opposite effects of MgADP Mol Pharmacol	1999	Zeitschriftenbeitrag	Hambrock A, Löffler-Walz C, Kloor D, Delabar U, Horio Y, Kurachi Y, Quast U
Coexpression with the inward rectifier K+ channel Kir6.1 increases the affinity of the vascular sulfonylurea receptor SUR2B for glibenclamide Mol Pharmacol	1999	Zeitschriftenbeitrag	Russ U, Hambrock A, Artunc F, Löffler-Walz C, Horio Y, Kurachi Y, Quast U
Mg2+ and ATP dependence of KATP channel modulator binding to the recom¬binant sulphonylurea receptor, SUR2B Br J Pharmacol	1998	Zeitschriftenbeitrag	Hambrock A, Löffler-Walz C, Kurachi Y, Quast U
Binding and effects of KATP channel openers in the vascular smooth muscle cell line, A10 Br J Pharmacol	1997	Zeitschriftenbeitrag	Russ U, Metzger F, Kickenweiz E, Hambrock A, Krippeit-Drews P, Quast U