Anionically induced domino reactions; synthesis of analogues of marine sesquiterpenes
- Publikations-Art
- Zeitschriftenbeitrag
- Autoren
- Gutke, H.-J.; Oesterreich, K.; Spitzner, D.; Braun, N. A.
- Erscheinungsjahr
- 2001
- Veröffentlicht in
- Tetrahedron
- Band/Volume
- 57/6
- Seite (von - bis)
- 997-1003
An anionically induced domino reaction is the key step in the synthesis of the isotwistane skeleton. This precursor can be transformed into the marine sesquiterpene 2-isocyanopupukeanane or its structural analogs. The tricyclic ester I which is an analog of 2-pupukeanone was made by a new synthesis using tricyclo[3.2.1.02,7]octane as a synthon. The anionically induced domino reaction is the key step in this sequence.