Anionically induced domino reactions; synthesis of analogues of marine sesquiterpenes

Publication Type: Journal contribution
Authors: Gutke, H.-J.; Oesterreich, K.; Spitzner, D.; Braun, N. A.
Year of publication: 2001
Published in: Tetrahedron
Band/Volume: 57/6
Page (from - to): 997-1003

Abstract

An anionically induced domino reaction is the key step in the synthesis of the isotwistane skeleton. This precursor can be transformed into the marine sesquiterpene 2-isocyanopupukeanane or its structural analogs. The tricyclic ester I which is an analog of 2-pupukeanone was made by a new synthesis using tricyclo[3.2.1.02,7]octane as a synthon. The anionically induced domino reaction is the key step in this sequence.

Involved institutions

Institute of Chemistry
Bioorganic Chemistry