Bioassay guided isolation of a new C18-polyacetylene, (+)-9(Z),17-octadecadiene-12,14-diyne-1,11,16-triol, from Cussonia barterii
- Publikations-Art
- Zeitschriftenbeitrag
- Autoren
- Papajewski, S.; Guse, J.-H.; Klaiber, I.; Roos, G.; Suessmuth, R.; Vogler, B.; Walter, C. U.; Kraus, W.
- Erscheinungsjahr
- 1998
- Veröffentlicht in
- Planta Med. (1998), 64(5), 479-481
- Band/Volume
- 64/5
- Seite (von - bis)
- 479-81
A novel C18-polyacetylene, (+)-9(Z),17-octadecadiene-12,14-diyne-1,11,16-triol, has been isolated from the Et acetate ext. of Cussonia barterii (Araliaceae) leaves collected in Cameroon. The structure detn. was achieved by NMR, mass, IR, and UV spectroscopy. The new polyenyne shows antibacterial activity against Bacillus subtilis and Pseudomonas fluorescens, antifungal activity against Cladosporium cucumerinum, molluscicidal activity against Biomphalaria glabrata at low concns., and in addn. it possesses hemolytic activity.