Cytotoxic components from the bark of Stauranthus perforatus from Monteverde, Costa Rica

Publikations-Art
Zeitschriftenbeitrag
Autoren
Setzer, W. N.; Setzer, M. C.; Schmidt, J. M.; Moriarity, D. M.; Vogler, B.; Reeb, S.; Holmes, A. M.; Haber, W. A.
Erscheinungsjahr
2000
Veröffentlicht in
Planta Med.
Band/Volume
66/5
ISBN / ISSN / eISSN
0032-0943
Seite (von - bis)
493-494
Abstract

The crude dichloromethane ext. of Stauranthus perforatus stem bark showed in-vitro cytotoxic activity against Hep-G2 (human hepatocellular carcinoma) and MDA-MB-231 (human mammary adenocarcinoma) cells. The cytotoxic compds. proved to be the quinoline alkaloids skimmianine and veprisine, and the furocoumarin heraclenin. Other compds. isolated included .beta.-sitosterol, isopimpinellin, and xanthotoxin

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