Cytotoxic components from the bark of Stauranthus perforatus from Monteverde, Costa Rica

Publication Type: Journal contribution
Authors: Setzer, W. N.; Setzer, M. C.; Schmidt, J. M.; Moriarity, D. M.; Vogler, B.; Reeb, S.; Holmes, A. M.; Haber, W. A.
Year of publication: 2000
Published in: Planta Med.
Band/Volume: 66/5
ISBN / ISSN / eISSN: 0032-0943
Page (from - to): 493-494

Abstract

The crude dichloromethane ext. of Stauranthus perforatus stem bark showed in-vitro cytotoxic activity against Hep-G2 (human hepatocellular carcinoma) and MDA-MB-231 (human mammary adenocarcinoma) cells. The cytotoxic compds. proved to be the quinoline alkaloids skimmianine and veprisine, and the furocoumarin heraclenin. Other compds. isolated included .beta.-sitosterol, isopimpinellin, and xanthotoxin

Involved persons

Sabine Mika

Involved institutions

Institute of Chemistry
Bioorganic Chemistry