Stereocontrolled synthesis of the key intermediate for the enantioselective synthesis of clerodane natural products
- Publikations-Art
- Zeitschriftenbeitrag
- Autoren
- Kato, M.; Kosugi, H.; Kodaira, A.; Hagiwara, H.; Vogler, B.
- Erscheinungsjahr
- 1997
- Veröffentlicht in
- Tetrahedron Lett. (1997), 38(39), 6845-6848
- Band/Volume
- 28/39
- Seite (von - bis)
- 6845-48
Stereocontrolled synthesis of (+)-trans-decalone I from (-)-verbenone, readily obtainable from (+)-nopinone, is described. The compd. I possesses four correctly arranged chiral centers, C(5)-C(10)-C(9)-C(8), necessary for the enantioselective synthesis of neo-trans-clerodanes.