Stereocontrolled synthesis of the key intermediate for the enantioselective synthesis of clerodane natural products

Publication Type
Journal contribution
Authors
Kato, M.; Kosugi, H.; Kodaira, A.; Hagiwara, H.; Vogler, B.
Year of publication
1997
Published in
Tetrahedron Lett. (1997), 38(39), 6845-6848
Band/Volume
28/39
Page (from - to)
6845-48
Abstract

Stereocontrolled synthesis of (+)-trans-decalone I from (-)-verbenone, readily obtainable from (+)-nopinone, is described. The compd. I possesses four correctly arranged chiral centers, C(5)-C(10)-C(9)-C(8), necessary for the enantioselective synthesis of neo-trans-clerodanes.

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