Guanylcobamide and hypoxanthylcobamide. Corrinoids formed by Desulfovibrio vulgaris

Publication Type: Journal contribution
Authors: Guimares, D. H.; Weber, A.; Klaiber, I.; Vogler, B.; Renz, P.
Year of publication: 1994
Published in: Arch. Microbiol.
Band/Volume: 162/4
Page (from - to): 272-6

Abstract

The corrinoids synthesized by the sulfate-reducing bacterium Desulfovibrio vulgaris were analyzed. The compds. found were guanylcobamide (I) and hypoxanthylcobamide (II); structures were detd. by mass spectrometry, 1H-NMR, and UV/visible spectroscopy. D. vulgaris used externally added guanine to form guanylcobamide, as demonstrated with 8-14C-guanine. Addn. of adenine did not lead to the formation of adenylcobamide (pseudovitamin B12), whereas 5,6-dimethylbenzimidazole was transformed into vitamin B12.

Involved persons

Iris Klaiber

Involved institutions

Institute of Chemistry
Bioorganic Chemistry