LC-Coupeled spectroscopic studies of Angelica dahurica and Ligusticum chianxiong with emphasis on LC-NMR
- Publication Type
- Contribution to conference
- Authors
- Bauer, R.; Klaiber, I.; Vogler, B.; Zschocke, S.
- Year of publication
- 1998
- Published in
- Quality of Medicinal Plants and Herbal Medicinal Products
- Editor
- Gesellschaft für Arzneimittelforschung
- Series/labeling
- Abstracts of Plenary Lectures, Short Lectures and Posters
- Page (from - to)
- SL07
- Conference name
- 46th Annual Congress of the Society of Medicinal Plant Research
- Conference location
- Wien
- Conference date
- 31.08.-04.09.1998
There is inscreasing demand in Western countries for knowledge about drug usage in Traditional Chinese Medicine (TCM. This is because of the wide application of such drugs which make their usage attractive as alternative therapy. A detailed scientific examination is the basis for a safe and rational use of Chinese drugs in Western countries.The first priority is to establish riliable and reproducible analytical procedures in order to characterize the plant extracts. In routine laboratory investigations HPLC isprobaly the most important tool for a fast indentification of drug constituents. Nowadays there are promising results from LC-coupeld spectroscopic methods which allow structure elucidation without preceding isolation. Already ug-quantities of compounds can be studied by HPLC-UV, HPLC-MS and by HPLC-NMR as well. The presentation will emphasize on LC-NMR in order to demonstrate the potential of this newly established method.Furthermore we would like to show the benefits of the combines usage of these techniques, which enabled us to assign the structures of the main constituents of two frequently used Chinese dugs: Radix angelicae dahuricae and Rhizoma Lingustici chuanxiong (Apiaceae).