Synthesis of Functionalized Naphthalenes by Copper(I)-Catalyzed Annulation between 3-(2-Halobenzyl)pentane-2,4-diones and β-Ketoesters, Malonates and Cyanoacetates

Publication Type
Journal contribution (peer reviewed)
Authors
Sudheendran, K; Malakar, C. C.; Conrad, J.; Beifuss, U.
Year of publication
2013
Published in
Adv. Synth. Catal.
Band/Volume
355/
DOI
10.1002/adsc.201300372
Page (from - to)
2400-2416
Abstract

The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%.

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