One-pot reactions: enantiomerically pure bicyclo[5.3.1]undecanes; synthesis of a taxoid compound

Publication Type: Journal contribution
Authors: Gutke, H.-J.; Braun, N. A.; Spitzner, D.
Year of publication: 2004
Published in: Tetrahedron
Band/Volume: 60/37
Page (from - to): 8137-8141

Abstract

Reaction of C-2 substituted cyclohexenone with an enantiomerically pure a-bromopentenoate leads to enantiopure tricyclooctane, which can be transformed into a taxoid like compd. having the typical bicyclo[5.3.1]undecane skeleton.

Involved institutions

Institute of Chemistry
Bioorganic Chemistry