Triethyl phosphite mediated domino reaction: direct conversion of ϖ-nitroalkenes into N-heterocycles
- Publication Type
- Journal contribution (peer reviewed)
- Authors
- Merisor, E.; Conrad, J.; Klaiber, I.; Mika, S.; Beifuss, U.
- Year of publication
- 2007
- Published in
- Angew. Chem. Int. Ed.
- Band/Volume
- 46/18
- DOI
- 10.1002/anie.200605260
- Page (from - to)
- 3353-3355
The first domino reaction in which ϖ-nitroalkenes are converted into satd. N-heterocycles is described. The reductive cyclization reaction mediated by tri-Et phosphite allows access to substituted 3,4-dihydro-2H-1,4-benzoxazines, 1,2,3,4-tetrahydroquinoxalines, and 1,2,3,4-tetrahydroquinolines.